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| 平台 | ROM名称 | 游戏名称 | 中文名称 | 补充 |
|---|---|---|---|---|
| gb | Roger Clemens' MVP Baseball (USA) | Roger Clemens' MVP Baseball (USA) | MVP棒球 | |
| gb | Rolan's Curse (USA) | Rolan's Curse (USA) | 罗兰的诅咒 | |
| gb | Rolan's Curse II (USA) | Rolan's Curse II (USA) | 罗兰的诅咒2 | |
| gb | Rubble Saver (Japan) | Rubble Saver (Japan) | 原子机器童 | |
| gb | Rubble Saver II (Japan) | Rubble Saver II (Japan) | 原子机器童2 | |
| gb | Rugrats Movie, The (USA) (SGB Enhanced) | Rugrats Movie, The (USA) (SGB Enhanced) | 淘气小兵兵 | |
| gb | Sa-Ga 2 - Hihou Densetsu (Japan) (Rev 1) | Sa-Ga 2 - Hihou Densetsu (Japan) (Rev 1) | 浪漫沙加2-秘宝传说 | |
| gb | Sa-Ga 2 - Hihou Densetsu (Japan) | Sa-Ga 2 - Hihou Densetsu (Japan) | 浪漫沙加2-秘宝传说 | |
| gb | Sa-Ga 2 - Hihou Densetsu (World) (Ja) (Rev 1) (Collection of SaGa) | Sa-Ga 2 - Hihou Densetsu (World) (Ja) (Rev 1) (Collection of SaGa) | 浪漫沙加2-秘宝传说 | |
| gb | Sa-Ga 3 - Jikuu no Hasha (Japan) | Sa-Ga 3 - Jikuu no Hasha (Japan) | 浪漫沙加3-时空霸者 | |
| gb | Sa-Ga 3 - Jikuu no Hasha (World) (Ja) (Collection of SaGa) | Sa-Ga 3 - Jikuu no Hasha (World) (Ja) (Collection of SaGa) | 浪漫沙加3-时空霸者 | |
| gb | Sagaia (Japan) | Sagaia (Japan) | 太空战斗机 | |
| gb | Saigo no Nindou (Japan) | Saigo no Nindou (Japan) | 最后忍道 | |
| gb | Saint Paradise - Saikyou no Senshi-tachi (Japan) | Saint Paradise - Saikyou no Senshi-tachi (Japan) | 圣斗士星矢-最强战士 | |
| gb | Sakigake!! Otoko Juku - Meioutou Kessen (Japan) | Sakigake!! Otoko Juku - Meioutou Kessen (Japan) | 魁男塾 | |
| gb | Same Game (Japan) (SGB Enhanced) | Same Game (Japan) (SGB Enhanced) | 相似方块 | |
| gb | Samurai Shodown (USA, Europe) (SGB Enhanced) | Samurai Shodown (USA, Europe) (SGB Enhanced) | 侍魂 | |
| gb | Sangokushi - Game Boy Ban (Japan) | Sangokushi - Game Boy Ban (Japan) | 三国志 | |
| gb | Sanrio Carnival (Japan) | Sanrio Carnival (Japan) | 凯蒂猫方块 | |
| gb | Sanrio Carnival 2 (Japan) | Sanrio Carnival 2 (Japan) | 凯蒂猫方块2 | |
| gb | Sanrio Uranai Party (Japan) (Rev 1) | Sanrio Uranai Party (Japan) (Rev 1) | 凯蒂猫派对 | |
| gb | Sanrio Uranai Party (Japan) | Sanrio Uranai Party (Japan) | 凯蒂猫派对 | |
| gb | Schiffe Versenken (Germany) (En,Fr,De,Es) | Schiffe Versenken (Germany) (En,Fr,De,Es) | 大海战 | |
| gb | Scotland Yard (Japan) | Scotland Yard (Japan) | 伦敦警察局 | |
| gb | SD Gundam - SD Sengokuden - Kunitori Monogatari (Japan) | SD Gundam - SD Sengokuden - Kunitori Monogatari (Japan) | SD高达外传-骑士物语 | |
| gb | SD Gundam Gaiden - Lacroan' Heroes (Japan) | SD Gundam Gaiden - Lacroan' Heroes (Japan) | SD高达外传 | |
| gb | SD Hiryuu no Ken Gaiden (Japan) (SGB Enhanced) | SD Hiryuu no Ken Gaiden (Japan) (SGB Enhanced) | SD飞龙之拳外传 | |
| gb | SD Hiryuu no Ken Gaiden 2 (Japan) (SGB Enhanced) | SD Hiryuu no Ken Gaiden 2 (Japan) (SGB Enhanced) | SD飞龙之拳外传2 | |
| gb | SD Lupin Sansei - Kinko Yaburi Daisakusen (Japan) | SD Lupin Sansei - Kinko Yaburi Daisakusen (Japan) | SD鲁邦三世-金库破大作战 | |
| gb | SD Sengokuden 2 - Tenka Touitsu Hen (Japan) | SD Sengokuden 2 - Tenka Touitsu Hen (Japan) | SD战国传2-天下统一 | |
| gb | SD Sengokuden 3 - Chijou Saikyou Hen (Japan) | SD Sengokuden 3 - Chijou Saikyou Hen (Japan) | SD战国传3-地上最强篇 | |
| gb | Sea Battle (Europe) (En,Fr,De,Es) | Sea Battle (Europe) (En,Fr,De,Es) | 大海战 | |
| gb | seaQuest DSV (USA, Europe) (SGB Enhanced) | seaQuest DSV (USA, Europe) (SGB Enhanced) | 深海巡弋 | |
| gb | Seaside Volley (Japan) | Seaside Volley (Japan) | 沙滩排球 | |
| gb | Seiken Densetsu - Final Fantasy Gaiden (Japan) (Seiken Densetsu Collection) | Seiken Densetsu - Final Fantasy Gaiden (Japan) (Seiken Densetsu Collection) | 圣剑传说-最终幻想外传 | |
| gb | Seiken Densetsu - Final Fantasy Gaiden (Japan) | Seiken Densetsu - Final Fantasy Gaiden (Japan) | 圣剑传说-最终幻想外传 | |
| gb | Selection - Erabareshi Mono (Japan) | Selection - Erabareshi Mono (Japan) | 抉择 | |
| gb | Selection I & II - Erabareshi Mono & Ankoku no Fuuin (Japan) (SGB Enhanced) | Selection I & II - Erabareshi Mono & Ankoku no Fuuin (Japan) (SGB Enhanced) | 抉择1+2 | |
| gb | Selection II - Ankoku no Fuuin (Japan) | Selection II - Ankoku no Fuuin (Japan) | 抉择2 | |
| gb | Sengoku Ninja-kun (Japan) | Sengoku Ninja-kun (Japan) | 战国忍者君 | |
| gb | Sensible Soccer - European Champions (Europe) | Sensible Soccer - European Champions (Europe) | 感官足球 | |
| gb | Serpent (USA) | Serpent (USA) | 大蛇 | |
| gb | Shadow Warriors (Europe) | Shadow Warriors (Europe) | 暗影武士 | |
| gb | Shanghai (Japan) (Activision) | Shanghai (Japan) (Activision) | 上海 | |
| gb | Shanghai (Japan) (HAL Laboratory) | Shanghai (Japan) (HAL Laboratory) | 上海 | |
| gb | Shanghai (USA) | Shanghai (USA) | 上海 | |
| gb | Shanghai Pocket (Japan) (SGB Enhanced) | Shanghai Pocket (Japan) (SGB Enhanced) | 口袋上海 | |
| gb | Shaq Fu (USA) (SGB Enhanced) | Shaq Fu (USA) (SGB Enhanced) | 夏福 | |
| gb | Shikinjou (Japan) | Shikinjou (Japan) | 紫禁城 | |
| gb | Shin Keiba Kizoku Pocket Jockey (Japan) (SGB Enhanced) | Shin Keiba Kizoku Pocket Jockey (Japan) (SGB Enhanced) | 新竞马贵族 |